Chip28 protein
WebThese studies demonstrated: (i) CHIP28 water channel activity is retained despite substitution of individual cysteines with serine; (ii) cysteine 189 is the Hg(2+)-sensitive … WebThe same protein was purified by chance by Agre group in Baltimore, USA, in 1988, who called in 1991 the protein CHIP28 (CHannel forming Integral membrane Protein of 28 kDa), suggesting that it may play a role in linkage of the membrane skeleton to the lipid bilayer. In 1992 the Agre group identified CHIP28's water transport property.
Chip28 protein
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WebOct 30, 2006 · We have thus a world priority in the discovery of the first water channel in the RBC membrane, that was re-discovered by chance by the group of Agre (Baltimore, … WebCHIP28 is an abundant integral membrane protein in RBCs and renal tubules, and Xenopus laevis oocytes injected with CHIP28 RNA exhibit high osmotic water permeability, P f [Preston et al. (1992) Science 256, 385-387]. Purified CHIP28 from human RBCs was reconstituted into proteoliposomes in order to establish if CHIP28 is itself the functional ...
WebJan 1, 2001 · Abstract. CHIP28 is a 28-kDa integral membrane protein with similarities to membrane channels and is found in erythrocytes and renal tubules. A cDNA for CHIP28 was isolated from human fetal liver cDNA template by a three-step polymerase chain reaction (PCR) cloning strategy, starting with degenerate oligonucleotide primers corresponding … WebApr 1, 1992 · The CHIP28 protein is an abundant integral membrane protein in mammalian RBCs and renal proximal tubules and belongs to a family of membrane proteins with unknown functions. Oocytes from Xenopus laevis microinjected with in vitro-transcribed CHIP28 RNA exhibited increased osmotic water permeability; this was reversibly …
http://globalauthorid.com/WebPortal/ArticleView?wd=8FF74A1A4A11A080E5016857A7F89C65960096180EA0F114 WebJan 2, 1993 · The sites of water transport along the nephron are well characterized, but the molecular basis of renal water transport remains poorly understood. CHIP28 is a 28-kD …
WebAug 15, 2002 · Salt stress (200 mM NaCl) down-regulated HvPIP2;1 (transcript and protein), but had almost no effect on the expressions of HvPIP1;3, ... some modifications of HvPIP2;1 protein. In animal aquaporins, glycosylated-AQP1 (formerly called CHIP28) was reported (Denker et al. 1988, Preston et al. 1992). Glycosylation at Asn-42 ...
WebQuick Reference. An abbreviation for CHannel-forming Integral Protein of 28 kDa relative molecular mass. CHIP-28 was purified from the plasma membranes of human … ct urogram other nameWebWater channels provide the plasma membranes of red cells and renal proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Molecular identification of CHIP28 protein as the membrane water channel was first accomplished by measurement of osmotic swelling of Xenopus oocytes injected with … easeus winpeWebCHIP28 is found in basolateral and apical plasma membranes of kidney proximal tubules and thin descending limbs of Henle, whereas WCH-CD is apically located in collecting duct principal cells. So far, the putative water channel that may be responsible for the high constitutive permeability of principal cell basolateral membranes has not been ... easeus winpe editionWebThe native CHIP28 protein is a noncovalent assembly of four subunits (12) and is physically similar to certain membrane channels (hence, CHIP28 = channel-forming integral protein of 28 kD). The cDNA encoding CHIP28 has been isolated (13), and the deduced amino acid sequence predicts an integral membrane protein with six bilayerspanning domains ... easeus winpe creatorWebProtein-coding gene in the species Homo sapiens AQP1 Available structures PDB Ortholog search: PDBeRCSB List of PDB id codes 4CSK, 1FQY, 1H6I, 1IH5 Identifiers Aliases AQP1, AQP-CHIP, CHIP28, CO, … easeus winpe bootableWeb(Figure omitted) The CHIP28 protein is related to the major intrinsic protein from bovine lens, MIP26, a channel through which lens fiber cells may absorb interstitial fluid (14). … easeus winpe isoWebAug 25, 1992 · Water rapidly crosses the plasma membranes of red blood cells (RBCs) and renal tubules through highly specialized channels. CHIP28 is an abundant integral membrane protein in RBCs and renal tubules, and Xenopus laevis oocytes injected with CHIP28 RNA exhibit high osmotic water permeability, Pf [Preston et al. (1992) Science … easeus windows 10 migration tool