WebSep 21, 2024 · Cyclophosphamide is a white crystalline powder with the molecular formula C 7 H 15 Cl 2 N 2 O 2 P•H 2 O and a molecular weight of 279.1. The chemical name for cyclophosphamide is 2- [bis (2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate. Web아프레피탄트(aprepitant)는 에멘드(Emend) 등의 상품명으로 판매되는 약물로, 화학요법 유발성 오심 및 구토(CINV)와 수술후 오심 및 구토(PONV)를 막기 위해 사용된다. 온단세트론이나 덱사메타손과 함께 투여할 수도 있다. 경구나 정맥 주사로 투여한다.. 흔한 부작용에는 피로감, 식욕부진, 설사, 복통 ...
Effect of temperature on the structure and drug-release …
WebPhosphate esters have the general structure P (=O) (OR) 3 feature P (V). Such species are of technological importance as flame retardant agents, and plasticizers. Lacking a P−C bond, these compounds are in the technical sense not organophosphorus compounds but esters of phosphoric acid. WebJan 17, 2012 · Cyclophosphamide and ifosfamide are alkylating agents administered to treat malignant disease. They are prodrugs and require activation by hepatic microsomal … fast tax refund hartwell ga
Cyclophosphamide - Wikipedia
WebEvofosfamide is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard conjugated with 2-nitroimidazole, with potential antineoplastic activity.When exposed to hypoxic conditions, such as those found in hypoxic tumors, the 2-nitroimidazole moiety of evofosfamide is reduced. This releases the DNA-alkylating Br-IPM moiety, … WebIn this study, we performed molecular dynamics simulations of the inclusion complex of β-CD with cyclophosphamide (CP) at temperatures from 300 K to 400 K to investigate … WebCyclophosphamide is a nitrogen mustard that acts as alkylating agent . In-vivo, it is splitted into phosphoramide mustard and acrolein by metabolism in the liver. The former is responsible for... fast tax refund advance