Description of ovariectomy protocol in mice
WebJul 1, 2011 · Dorsal ovariectomy is a quick and simple procedure to perform on rodent patients. This procedure can be used to both prevent and treat many common diseases of the female rodent reproductive tract. It has also been shown to prevent mammary and pituitary tumors in rats. Although this article describes how to perform a dorsal … WebDescription of Ovariectomy Protocol in Mice Vanessa R. Souza, Eduardo Mendes, Mateus Casaro, Ana Tada F. B. Antiorio, Fernando A. Oliveira, and Caroline M. Ferreira ... Despite the diversity of ovariectomy protocols, the aim of this chapter is to provide a comprehensive guideline in performing ovariectomy in mice. Furthermore, isoflur-
Description of ovariectomy protocol in mice
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WebJul 1, 2011 · How to Perform Dorsal Rodent Ovariectomy. 1. Anesthetize the patient using standard techniques. Include analgesia in the anesthetic protocol. 2. Place the animal in ventral recumbency and clip the fur in a square centered at approximately the third lumbar vertebra. The square should extend 2 to 3 cm lateral to the dorsal spinous process. WebMar 17, 2014 · Germ-free mice have increased bone mass associated with reduced bone resorption indicating that the GM also regulates bone mass. Ovariectomy (ovx) results …
WebThis chapter describes the surgical procedures for ovariectomy and orchidectomy in mice and rats. In -addition to providing technical details of the surgical techniques, details of … WebAug 29, 2024 · In the experiment, the 8-week-old mice underwent ovariectomy to induce female osteoporosis, and equal numbers of mice underwent a sham operation after adaptation. All mice in the OVX group underwent bilateral ovariectomy, and those in the sham surgery group underwent the same procedure except that the ovaries were …
WebThis chapter describes the surgical procedures for ovariectomy and orchiectomy in mice and rats. In addition to providing technical details of the surgical techniques, details of … WebMar 4, 2024 · In preclinical research, ovariectomy in mice and rats is used as a surgical menopausal model to study the effects of the permanent reduction in the levels of steroid …
WebJun 7, 2012 · Abstract Estrogens are a family of female sexual hormones with an exceptionally wide spectrum of effects. When rats and mice are used in estrogen research they are commonly ovariectomized in order to ablate the rapidly cycling hormone production, replacing the 17β-estradiol exogenously.
WebNational Center for Biotechnology Information how clean car seatsWebDec 4, 2009 · The goal of this study was to characterize the skeletal response to ovariectomy in mice (129P3, C57BL/6, and B6129PF2) commonly used in gene manipulation studies to evaluate their potential as preclinical models of postmenopausal osteoporosis. ... Experimental protocol. Mice in each strain were randomized by weight … how clean car interiorWebFrom: Description of Ovariectomy Protocol in Mice Female mice reproductive tract major components: ovaries and ductal system Back to protocol page how clean carpet with vinegarWebCurrent Protocols in Mouse Biology Bone is an essential organ that not only confers structural stability to the organism, but also serves as a reservoir for hematopoietic elements and is thought to affect systemic homeostasis through the release of endocrine factors as well as calcium. The loss of bone mass due to an uncoupling of bo … how clean chalkboardWebFeb 11, 2024 · Female reproductive system. An oophorectomy (oh-of-uh-REK-tuh-me) is a surgical procedure to remove one or both of your ovaries. Your ovaries are almond-shaped organs that sit on each side of the uterus in your pelvis. Your ovaries contain eggs and produce hormones that control your menstrual cycle. When an oophorectomy involves … how clean ceiling fanWebOct 1, 2012 · This chapter describes the surgical procedures for ovariectomy and orchiectomy in mice and rats. In addition to providing technical details of the surgical techniques, details of anesthesia ... how clean carburetorWebIn contrast, in the C57BL mice, ovariectomy caused a marked increase in fecal calcium (84.5%, p < 0.01), and a marked decrease in the amount (55%, p < 0.01) and percentage (34.8%, p < 0.001) of calcium absorbed, and the decrease in the percentage of calcium absorbed was partially prevented by E 2 therapy how clean carpet at home